University of Minnesota

Ancel Keys and Mark Hegsted Letters 1986

Toward the end of their lives, Mark Hegsted and Ancel Keys got closer together about the shape of the relation of dietary cholesterol and serum cholesterol. They were always together on the relation of dietary oleic acid and serum cholesterol. Their careful study designs allowed them to see that, other factors constant, oleic acid was neutral in effect on serum cholesterol. Mattson and Grundy held out that oleic lowered serum cholesterol, whereas their design only showed a lowering effect as replacement for saturated fatty acids. This they misinterpreted as an independent lowering effect like PUFA. These letters show their postures along with mutual respect.

Click below to download letters:

Hegsted: 1986-03-03 Letter Hegsted-Keys

Keys: 1986-03-19 Letter Keys-Hegsted

Related Content

Bio Sketch(es)