James S. Pankow, Ph.D., M.P.H.
Associate Professor
Epi Major Chair
Doctor of Philosophy in Epidemiology, University of Minnesota,
Minneapolis, MN
Master of Public Health in Epidemiology, University of Minnesota,
Minneapolis, MN
Bachelor of Science in Biological Sciences, University of Notre Dame, Notre Dame, IN
Teaches:
PubH 6342 Epidemiologic Methods II
Research Interests:
Cardiovascular disease epidemiology, genetic epidemiology, diabetes epidemiology
>>> Research Projects
Recent Publications:
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Bielinski S, Pankow JS, Hopkins P, Eckfeldt J, Hixson J, Liu Y, Register T, Myers R, Arnett D. Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on Chromosome 19: the NHLBI Family Heart Study Follow-up Examination. Atherosclerosis 2008; 199(1): 172-178. PMCID: PMC2517220
Moran A, Jacobs DR, Steinberger J, Steffen LM, Pankow JS, Hong CP, Sinaiko AR. Changes in insulin resistance and cardiovascular risk during adolescence: establishment of differential risk in males and females. Circulation 2008; 117: 2361-2368. PMID: 18427135
Yeh HC, Punjabi N, Wang NY, Pankow JS, Duncan BB, Cox CE, Selvin E, Brancati FL. Cross-sectional and prospective study of lung function in adults with type 2 diabetes mellitus: the Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care 2008; 31: 741-746. PMID: 18056886
Zhang Q, Lewis CE, Wagenknecht LE, Myers RH, Pankow JS, Hunt SC, North KE, Hixson JE, Carr JJ, Shimmin LC, Borecki I, Province MA. Genome-wide admixture mapping for coronary artery calcification in African Americans: the NHLBI Family Heart Study. Genetic Epidemiology 2008; 32: 264-272. PMID: 18200599
Bare LA, Morrison AC, Rowland CM, Shiffman D, Luke MM, Iakoubova OA, Kane JP, Malloy MJ, Ellis SG, Pankow JS, Willerson JT, Devlin JJ, Boerwinkle E. Five common gene variants identify elevated genetic risk for coronary heart disease. Genetics in Medicine 2007; 9: 682-689. PMID: 18073581
Folsom AF, Pankow JS, Peacock J, Bielinski S, Heiss G, Boerwinkle E. Variation in TCF7L2 and increased risk of colon cancer: The Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care 2008; 31: 905-909. PMCID: PMC2577771
Ballantyne CM, Hoogeveen RC, McNeill AM, Heiss G, Schmidt MI, Duncan BB, Pankow JS. Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC Study. International Journal of Obesity (London) 2008; 32 (Suppl. 2): S21-24. PMID: 18469836
Bielinski SJ, Pankow JS, Li N, Hsu FC, Adar SA, Swords Jenny N, Bowden DW, Arnett D. ICAM1 and VCAM1 polymorphisms, coronary artery calcium, and circulating levels of soluble ICAM-1: The Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis 2008; 201(2): 339-344. PMCID: PMC2615541
Bielinski SJ, Pankow JS, Folsom AR, North KE, Boerwinkle E. TCF7L2 single nucleotide polymorphisms, cardiovascular disease, and all-cause mortality: The Atherosclerosis Risk in Communities (ARIC) Study. Diabetologia 2008; 51: 968-970. PMCID: PMC2597203
Sherva R, Miller MB, Pankow JS, Hunt SC, Boerwinkle E, Mosley TH, Weder AB, Curb JD, Luke A, Morrison AC, Fornage M, Arnett DK. A whole-genome scan for stroke or myocardial infarction in the Family Blood Pressure Program families. Stroke 2008; 39:1115-1120. PMID: 18323513
Bielinski SJ, Pankow JS, Boerwinkle E, Bray MS, Kao WHL, Folsom AR. Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the Atherosclerosis Risk in Communities Study (ARIC). Acta Diabetologica 2008; 45: 179-182. PMCID: PMC2586599
Köttgen A, Hwang SJ, Rampersaud E, Coresh J, North KE, Pankow JS, Meigs JB, Florez JC, Parsa A, Levy D, Boerwinkle E, Shuldiner AR, Fox CS, Kao WHL. TCF7L2 variants associate with CKD progression and renal function population-based cohorts. Journal of the American Society of Nephrology 2008; 19: 1989-1999. PMCID: PMC2551569
Tamariz LJ, Young JH, Pankow JS, Yeh HC, Schmidt MI, Astor B, Brancati FL. Blood viscosity and Hematocrit as risk factors for type 2 diabetes mellitus: The Atherosclerosis Risk in Communities Study. American Journal of Epidemiology 2008; 168: 1153-1160. PMCID: PMC 2581671
Pankow JS, Boerwinkle E, Adams PC, Guallar E, Leiendecker-Foster C, Rogowski J, Eckfeldt JH. HFE C282Y homozygotes have reduced LDL cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study. Translational Research 2008; 152: 3-10. PMCID: PMC 2581671
Rasmussen-Torvik LJ, Pankow JS, Jacobs DR Jr, Steinberger J, Moran A, Sinaiko AR. Influence of waist on adiponectin and insulin sensitivity in adolescence. Obesity 2009; 17: 156-161. PMID: 19107128
Yan Y, North KE, Ballantyne CM, Brancati FL, Chambless LE, Franceschini N, Heiss G, Köttgen A, Pankow JS, Selvin E, West SL, Boerwinkle E. Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities Study (ARIC). Diabetes 2009; 58: 285-289. PMCID: PMC 2587433
Feitosa MF, Myers RH, Pankow JS, Province MA, Borecki IB. LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion. In press, Atherosclerosis 2008. PMID: 19101670
Scheuner MT, Setodji CM, Pankow JS, Blumenthal RS, Keeler E. Relation of familial patterns of coronary heart disease, stroke, and diabetes to subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis. Genetics in Medicine 2008; 10: 879-887. PMID: PMC2684807
Meyer TE, Shiffman D, Morrison AC, Rowland CM, Louie JZ, Bare LA, Ross D, Arellano AR, Catanese JJ, Ridker PM, Pankow JS, Coresh J, Malloy MJ, Kane JP, Ellis SG, Devlin JJ, Boerwinkle E. A GOSR2 LYS67ARG variant is associated with hypertension in whites. American Journal of Hypertension 2009; 22: 163-168. PMID: 19057520
Shi G, Gu CC, Kraja AT, Arnett DK, Myers RH, Pankow JS, Hunt SC, Rao DC. Genetic effect on blood pressure is modulated by age: The HyperGEN Study. Hypertension 2009; 53: 35-41. PMCID: PMC 2633773
Rasmussen-Torvik LJ, Pankow JS, Jacobs DR Jr, Steinberger J, Moran A, Sinaiko A. SNPS in ADIPOQ, ADIPOR1, and ADIPOR2 are associated with insulin sensitivity in a cohort of adolescents and their parents. Human Genetics 2009; 125: 21-28. PMID: 19037660
Adams PC, Pankow JS, Barton JC, Acton RT, Leiendecker-Foster C, McLaren GD, Speechley M, Eckfeldt JH. HFE C282Y homozygosity is associated with lower total and LDL cholesterol: the Hemochromatosis and Iron Overload Screening (HEIRS) Study. In press, Circulation: Cardiovascular Genetics. PMID:
Dehghan A, Yang Q, Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen M-H, Baumert J, Lowe GDO, McKnight B, Tang W, de Maat M, Larson MG, Eyhermendy S, McArdle WL, Lumley T, Pankow JS, Hofman A, Massaro JM, Rivadeneira F, Kolz M, Taylor KD, van Duijn CM, Kathiresan S, Illig T, Aulchenko YS, Volcik KA, Uitterlinden A, Tofler GH, Gieger C, Welcome Trust Case Control Consortium, Psaty BM, Couper DJ, Boerwinkle E, Koenig W, O¹Donnell CJ, Witteman JC, Strachan DP, Smith NL, Folsom AR: Association of novel genetic loci with circulating fibrinogen levels: A genome-wide association study in six population-based cohorts. In press, Circulation: Cardiovascular Genetics. PMID:
Wu J, Pankow JS, Tracy RP, North KE, Myers RH, Feitosa ME, Province MA, Borecki IB. A QTL on 12q influencing an inflammation marker and obesity in white women: NHLBI Family Heart Study. Obesity 2009; 17: 525-531. PMID: 19238141
Morrison AC, Bare LA, Luke MM, Pankow JS, Mosley TH, Devlin JJ, Willerson JT, Boerwinkle E. Single nucleotide polymorphisms associated with coronary heart disease predict incident ischemic stroke in the Atherosclerosis Risk in Communities (ARIC) study. Cerebrovascular Diseases 2008; 26: 420-424. PMCID: PMC 2662496
Franceschini N, North KE, Arnett D, Pankow JS, Chung JH, Baird L, Leppert MF, Eckfeldt JH, Boerwinkle E, Gu CC, Lewis CE, Myers RH, Turner ST, Weder A, Kao WH, Mosley TH, Chakravarti A, Kramer H, Hunt SC. The association of cell cycle Checkpoint 2 variants and kidney function: findings from the Family Blood Pressure Study and the Atherosclerosis Risk in Communities Study. American Journal of Hypertension 2009; 22: 552-558. PMID: 19265784
Basu S, Stephens M, Pankow JS, Thompson EA. A likelihood-based trait-model-free approach for linkage detection of binary trait. In press, Biometrics. PMID: 19459835
Lutsey PL, Pankow JS, Bertoni AG, Szklo M, Folsom AR. Serological evidence of infections and type 2 diabetes: The MultiEthnic Study of Atherosclerosis. Diabetic Medicine 2009; 26: 149-152. PMID: 19236617
Rule AD, Fridley BL, Hunt SC, Asmann Y, Boerwinkle E, Pankow JS, Mosley TH, Turner ST. Genome-wide linkage analysis for uric acid in families enriched for hypertension. Nephrology Dialysis Transplantation 2009; 24: 2414-2420. PMID: 19258383
Rasmussen-Torvik LJ, Pankow JS, Jacobs DR Jr, Sinaiko AR. No association between TCF7L2 rs7903146 and euglycemic-clamp derived insulin sensitivity in a mixed-age cohort. In press, Metabolism – Clinical and Experimental. PMID: 19573884
Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF, Aspelund T, Eiriksdottir G, Garcia M, Launer LJ, Smith AV, Mitchell BD, McArdle PF, Shuldiner AR, Bielinski SJ, Boerwinkle E, Brancati F, Demerath EW, Pankow JS, Arnold AM, Chen YD, Glazer NL, McKnight B, Psaty BM, Rotter JI, Amin N, Campbell H, Gyllensten U, Pattaro C, Pramstaller PP, Rudan I, Struchalin M, Vitart V, Gao X, Kraja A, Province MA, Zhang Q, Atwood LD, Dupuis J, Hirschhorn JN, Jaquish CE, O’Donnell CJ, Vasan RS, White CC, Aulchenko YS, Estrada K, Hofman A, Rivadeneira F, Uitterlinden AG, Witteman JC, Oostra BA, Kaplan RC, Gudnason V, O’Connell JR, Borecki IB, van Duijn CM, Cupples LA, Fox CS, North KE. NRXN3 is a novel locus for waist circumference: A genome-wide association study from the CHARGe consortium. PLOS Genetics 2009; 5: e1000539. PMID: 19557197
Caplan DJ, Pankow JS, Cai J, Offenbacher S, Beck JD. Relationship between self-reported history of root canal therapy and coronary heart disease in the ARIC Study. In press, Journal of the American Dental Association. PMID:
Weitzman S, Wang CH, Pankow JS, Schmidt MI, Brancati FL. Are measures of height and leg length related to incident diabetes mellitus? The ARIC (Atherosclerosis Risk in Communities) Study. In press, Acta Diabetologia. PMID:
Feitosa, MF, North KE, Myers RH, Pankow JS, Borecki IB. Evidence for three novel QTLs for adiposity on chromosome 2 with epistatic interactions: The NHLBI Family Heart Study. In press, Obesity. PMID: 19521348
Raynor LA, Pankow JS, Miller MB, Huang GH, Dalton D, Klein R, Klein BE, Cruickshanks KJ. Familial aggregation of age-related hearing loss in an epidemiological study of older adults. In press, American Journal of Audiology. PMID: 19474454
Rasmussen-Torvik LJ, Pankow JS, Peacock JM, Borecki IB, Hixson JE, Tsai MY, Kabagambe EK, Arnett DK. Suggestion for linkage of chromosome 1p35.2 and 3q28 to plasma adiponectin concentrations in the GOLDN Study. BMC Medical Genetics 2009;10:39. PMID: 19426517
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Professional Experience:
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Associate Professor, University of Minnesota, 2003-present
Assistant Professor, University of Minnesota, 2001-2003
Assistant Professor, University of North Carolina at Chapel Hill, 1997-2001
Consultant, Minneapolis Heart Institute, 1994-1995 |
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Honors:
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Delta Omega Honorary Society in Public Health, 1997
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Mailing Address:
Division of Epidemiology & Community Health
1300 South Second Street, Suite 300
Minneapolis, MN 55454-1015
Phone:(612) 624-2883
Or: Barb Lux, 626-9092, b-lux@umn.edu
Email: panko001@umn.edu
Office: 452 WBOB
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Link
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