Admin Support Services

Results from simulation modeling studies are increasingly being used along with results from epidemiologic studies to inform clinical guidelines and public health policies in the U.S. This has been particularly true in the area of human papillomavirus (HPV) and cervical cancer. This talk will provide a brief overview of decision models and illustrate how results from simulation modeling studies of HPV vaccines have identified areas for further research. References: Myers ER, McCrory DC, Nanda K, Bastian L, Matchar DB. Mathematical model for the natural history of human papillomavirus infection and cervical carcinogenesis. Am J Epidemiol. 2000;151:1158-71. Goldie SJ, Grima D, Kohli M, Wright TC, Weinstein M, Franco E. A comprehensive natural history model of HPV infection and cervical cancer to estimate the clinical impact of a prophylactic HPV-16/18 vaccine. Int J Cancer. 2003;106:896-904. Kulasingam S, Connelly L, Conway E, Hocking JS, Myers E, Regan DG, Roder D, Ross J, Wain G. A cost-effectiveness analysis of adding a human papillomavirus vaccine to the Australia National Cervical Cancer Screening Program. Sex Health. 2007;4:165-75.